Surgical tape can quickly bond body tissue, promising to replace surgical sutures
Release time：
Feb 29,2024
The Massachusetts Institute of Technology has invented a tape that can quickly close wounds and glue tissues together, potentially even affixing implantable medical devices to the target site. The researchers hope that the tape could eventually replace surgical sutures, which have many limitations.
There are more than 230 million major surgeries performed worldwide each year, many of which require suturing of wounds, which puts de facto pressure on tissues and can lead to infection, pain and scarring," the researchers said. We are introducing a very different approach to tissue suturing.
Sewing two moist tissue surfaces together is a challenging task. Sutures are not always suitable, especially for soft and delicate tissues - such as the lungs. Currently, surgeons utilise surgical glue as an alternative, but sometimes this glue takes several minutes to adhere and spreads or drips onto unwanted tissue.
The researchers were inspired by the sticky material that spiders use to trap insects. Such materials are sticky even in wet environments due to the presence of charged polysaccharides. The charged polysaccharides work by rapidly absorbing moisture from the surface, which dries the surface and allows adhesives to stick.
This new tape utilises polyacrylic acid to absorb moisture from the surface of the tissue to form a temporary bond. Then, a compound in the tape called an NHS ester forms a much stronger bond with the tissue proteins. Amazingly, the entire adhesion process takes just five seconds.
By varying the ratio of fast- and slow-degrading components, the researchers have succeeded in giving the tape both short- and long-term adhesion, and different types of tape can be used for specific purposes. Interestingly, the tape can also be used to adhere implantable medical devices. For example, the researchers successfully adhered a patch to a rat's heart.
"Such tapes offer a more decent, straightforward and generalised way of applying implantable monitors or drug delivery devices, as we are able to stick such devices to a variety of sites and without having to puncture the tissue, thus avoiding injury or secondary complications."
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Definition: Damage to normal skin (tissue) caused by external wound-causing factors such as surgery, external forces, heat, electric current, chemicals, low temperature, and intrinsic factors in the body such as impaired local blood supply.
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This method is the most basic of all bandages, and is used at the beginning and end of the bandage, as well as at the wrist, where the limb is of equal thickness.
When the situation is not serious, most people will only carry out simple treatment based on common sense, such as rinsing with water, simple disinfection, applying cold and hot compresses, and applying band-aids or gauze. Big-hearted friends even think that these small injuries and pains, do not deal with it does not matter, will naturally be fine.
